Wie Erwartungen die Schmerzverarbeitung beeinflussen
Prof. Dr. Ulrike Bingel (Projektleiterin A11) erforscht das Zusammenspiel von Schmerzverarbeitung im zentralen Nervensystem und kognitiven Prozessen. Eine zentrale Herausforderung ihrer Forschung ist die Frage, warum sich akute Schmerzen bei manchen Menschen chronifizieren, während andere wieder genesen – und wie personalisierte Behandlungsstrategien diesen unterschiedlichen Verläufen gerecht werden können.
Besonderes Augenmerk legt Bingel dabei auf Placebo- und Nocebo-Effekte, die auf messbaren neurobiologischen und physiologischen Mechanismen beruhen und nicht nur bei Placebo-Behandlungen eine Rolle spielen. Erwartungen können die Wirksamkeit und Verträglichkeit medizinischer Interventionen verbessern, aber auch Symptome und Nebenwirkungen verstärken – für Bingel sind Placebo-Effekte daher nicht nur eine Herausforderung für klinische Studien, sondern vielmehr eine therapeutische Ressource.
Als Sprecherin des DFG-geförderten SFB/TRR 289 „Treatment Expectation“ verbindet Bingel Grundlagenforschung mit der Entwicklung personalisierter Behandlungsansätze. Das Erwin L. Hahn Institute bietet dabei besondere Möglichkeiten, die neuronalen Mechanismen von Schmerz und Erwartung mit hochauflösender Bildgebung zu untersuchen.
New Year, New Me: The Facts
As the calendar turns to a new year, millions of people around the world commit to New Year’s resolutions, making promises to use the new year as a fresh beginning and an opportunity for transformation. In 2024, almost three-quarters of the British population set themselves New Year’s resolutions — that’s around 40 million people (or the entire population of Canada). This tradition was particularly strong among younger generations, with 96% of Generation Z (aged 18-27) planning resolutions, compared to just 35% of the Silent Generation (aged 79+).
Most common new years resolutions:
- Saving more money (52%)
- Eat healthier (50%)
- Exercise more (48%)
- Lose weight (37%)
- Spend more time with family/friends (35%)
How long do most resolutions normally last before being broken?
- Data from America (2016) shows that 75% of individuals maintain their resolutions through the first week.
- 64% of individuals maintain their resolutions through the first month.
- 46% of individuals in America keep their resolutions past the 6-month mark.
What makes resolutions stick?
Oscarsson et al. (2020) conducted research into what makes New Year’s resolutions stick. Biggest success rates depended on how people phrased their goals. Participants who set approach-oriented goals (trying to move toward or maintain a desirable outcome or state) than those with avoidance-oriented goals (trying to move toward or maintain a desirable outcome or state) were significantly more successful (58.9% vs. 47.1%) at sticking to their goals.
The study also investigates the effects of outside support. These participants received monthly follow-ups and emails with information and exercises for coping with hurdles when striving toward personal goals, and were also encouraged to set goals using the SMART technique and to set interim goals. The group that received some support was exclusively and significantly more successful compared to the groups who received a lot of support or no support at all.
Additionally, you might feel more successful if you set goals that are measurable in numbers. While success for a person striving to quit smoking or lose weight could easily be measured in the number of cigarettes smoked or body mass index, the success for a person striving to „take better care of themselves“ could be highly subjective and possibly impossible to measure.
So as we enter 2026, let’s remember to work with our brain’s natural learning system: Frame your goals positively, break them into manageable steps, and celebrate small wins along the way.