The translational project A16 “Early extinction learning and the developing brain” led by Silvia Schneider and Sarah Weigelt investigates the development of extinction in two critical times for major changes in the developing brain: infancy and adolescence. An innovative research design and state-of-the art neuro-developmental approaches allow the systematic research of qualitative and quantitative developmental transitions in extinction. The project translates for the first time findings from rodent research to humans and opens up future investigations with regard to therapeutic interventions.
Guiding questions of A16:
Konrad C, Herbert JS, Schneider S, Seehagen S (2016) Gist extraction and sleep in 12-month-old infants. Neurobiol Learn Mem. 134 Pt B: 216–220. doi:10.1016/j.nlm.2016.08.021
Konrad C, Herbert JS, Schneider S, Seehagen S (2016) The relationship between prior night’s sleep and measures of infant imitation. Dev Psychobiol. 58(4): 450–461. doi:10.1002/dev.21387
Konrad C, Seehagen S, Schneider S, Herbert JS (2016) Naps promote flexible memory retrieval in 12-month-old infants. Dev Psychobiol. doi:10.1002/dev.21431
Mosig C, Merz CJ, Mohr C, Adolph D, Wolf OT, Schneider S, Margraf J, Zlomuzica A (2014) Enhanced discriminative fear learning of phobia-irrelevant stimuli in spider-fearful individuals. Front Behav Neurosci. 8: 328. doi:10.3389/fnbeh.2014.00328
Seehagen S, Konrad C, Herbert JS, Schneider S (2015) Timely sleep facilitates declarative memory consolidation in infants. Proc Natl Acad Sci USA. 112(5): 1625–1629. doi:10.1073/pnas.1414000112
Seehagen S, Schneider S, Rudolph J, Ernst S, Zmyj N (2015) Stress impairs cognitive flexibility in infants. Proc Natl Acad Sci USA. 112(41): 12882–12886. doi:10.1073/pnas.1508345112
Semmelmann K, Nordt M, Sommer K, Rohnke R, Mount L, Prufer H, Terwiel S, Meissner TW, Koldewyn K, Weigelt S (2016) U Can Touch This: How Tablets Can Be Used to Study Cognitive Development. Front Psychol. 7: 1021. doi:10.3389/fpsyg.2016.01021
Vetter NC, Pilhatsch M, Weigelt S, Ripke S, Smolka MN (2015) Mid-adolescent neurocognitive development of ignoring and attending emotional stimuli. Dev Cogn Neurosci. 14: 23–31. doi:10.1016/j.dcn.2015.05.001
Vetter NC, Weigelt S, Dohnel K, Smolka MN, Kliegel M (2014) Ongoing neural development of affective theory of mind in adolescence. Soc Cogn Affect Neurosci. 9(7): 1022–1029. doi:10.1093/scan/nst081
Zlomuzica A, Preusser F, Schneider S, Margraf J (2015) Increased perceived self-efficacy facilitates the extinction of fear in healthy participants. Front Behav Neurosci. 9: 270. doi:10.3389/fnbeh.2015.00270