The translational project A16 “Early extinction learning and the developing brain” led by Silvia Schneider and Sarah Weigelt investigates the development of extinction in two critical times for major changes in the developing brain: infancy and adolescence. An innovative research design and state-of-the art neuro-developmental approaches allow the systematic research of qualitative and quantitative developmental transitions in extinction. The project translates for the first time findings from rodent research to humans and opens up future investigations with regard to therapeutic interventions.
Guiding questions of A16:
Konrad C, Adolph D, Herbert JS, Neuhoff L, Mohr C, Jagusch-Poirier J, Seehagen S, Weigelt S, Schneider S (2020) A New 3-Day Standardized Eyeblink Conditioning Protocol to Assess Extinction Learning From Infancy to Adulthood. Front Behav Neurosci. 14: 135.
Meissner TW, Walbrin J, Nordt M, Koldewyn K, Weigelt S (2020) Head motion during fMRI tasks is reduced in children and adults if participants take breaks. Dev Cogn Neurosci. 44: 100803.
Nordt M, Semmelmann K, Genç E, Weigelt S (2018) Age-related increase of image-invariance in the fusiform face area. Dev Cogn Neurosci. 31: 46–57.
Seehagen S, Schneider S, Sommer K, La Rocca L, Konrad C (2020) State-Dependent Memory in Infants. Child Dev.https://doi.org/10.1111/cdev.13444
Semmelmann K, Weigelt S (2018) Online webcam-based eye tracking in cognitive science: A first look. Behav Res. 50(2): 451–465.
Zlomuzica A, Schneider S, Konrad C, Merz CJ, Wolf OT, Raeder F, Margraf J (2020) Clinical implications of fear extinction in anxiety disorders. Neuroforum. 26(3): 143–149.